Psychosomatic medicine · 2006
Effects of naltrexone on repressive coping and disclosure of emotional material: a test of the opioid-peptide hypothesis of repression and hypertension.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Younger Jarred W, Lawler-Row Kathleen A, Moe Krista A, Kratz Anna L, Keenum Amy J
Аннотация
OBJECTIVE: The present study was designed to assess the role of endogenous opioids in the relationship of hypertension to repressive coping.
METHODS: Ten hypertensive and 8 normotensive males were given either the opioid antagonist naltrexone or placebo in a randomized, double-blind fashion over the course of four laboratory sessions. Measures of repression and disclosure were completed and blood pressure was assessed during a laboratory stressor protocol.
RESULTS: Opioid antagonism reduced repression and increased disclosure only in the hypertensive group. Also, opioid antagonism increased stress-related systolic blood pressure only in the hypertensive group.
CONCLUSION: The results support the hypothesis that endogenous opioid dysregulation underlies both hypertension and repressive phenomena.
METHODS: Ten hypertensive and 8 normotensive males were given either the opioid antagonist naltrexone or placebo in a randomized, double-blind fashion over the course of four laboratory sessions. Measures of repression and disclosure were completed and blood pressure was assessed during a laboratory stressor protocol.
RESULTS: Opioid antagonism reduced repression and increased disclosure only in the hypertensive group. Also, opioid antagonism increased stress-related systolic blood pressure only in the hypertensive group.
CONCLUSION: The results support the hypothesis that endogenous opioid dysregulation underlies both hypertension and repressive phenomena.
Предметные рубрики MeSH
Adaptation, PsychologicalAdultAffective SymptomsBlood PressureDouble-Blind MethodEmotionsFemaleHumansHypertensionMaleModels, PsychologicalNaltrexoneNarcotic AntagonistsOpioid PeptidesPsychological TestsRepression, PsychologySelf DisclosureSeverity of Illness IndexSurveys and QuestionnairesSympathetic Nervous System