Effects of naltrexone on repressive coping and disclosure of emotional material: a test of the opioid-peptide hypothesis of repression and hypertension.

OBJECTIVE

The present study was designed to assess the role of endogenous opioids in the relationship of hypertension to repressive coping.

METHODS

Ten hypertensive and 8 normotensive males were given either the opioid antagonist naltrexone or placebo in a randomized, double-blind fashion over the course of four laboratory sessions. Measures of repression and disclosure were completed and blood pressure was assessed during a laboratory stressor protocol.

RESULTS

Opioid antagonism reduced repression and increased disclosure only in the hypertensive group. Also, opioid antagonism increased stress-related systolic blood pressure only in the hypertensive group.

CONCLUSION

The results support the hypothesis that endogenous opioid dysregulation underlies both hypertension and repressive phenomena.