Hydramnios and observations in Bartter's syndrome.

A boy was born after a pregnancy complicated by a hydramnios. He appeared to suffer from Bartter's syndrome, a disease characterized by hyperreninemia, hyperaldosteronism and excess prostaglandin production resulting in hypokalemia, normotension, impaired urine concentration ability, polyuria and renal sodium loss. Other children with Bartter's syndrome, and also a different syndrome characterized by polyuria and hydramnios, are reviewed. In the evaluation of gross hydramnios of unknown etiology, Bartter's syndrome might also be considered.