Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases · 1998
[Significance of detecting E-selectin of serum and pleural effusion in differentiating benign and malignant diseases].
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Liu G, Li C, Zhong X
Аннотация
OBJECTIVE: To evaluate the significance of detecting E-selectin of serum and pleural effusion in differentiating benign and malignant diseases.
METHOD: E-selectin of serum and pleural effusion in 23 patients with tuberculous pleurisy and 21 patients with lung cancer involving pleura was detected by ELISA method.
RESULT: E-selectin of serum(44 +/- 5 micrograms/L) and pleural effusion (24 +/- 3 micrograms/L) in patients with tuberculous pleurisy was much higher than that of serum (27 +/- 4 micrograms/L) and pleural effusion (11 +/- 3 micrograms/L) in lung cancer patients (P < 0.01). In addition, E-selection of serum in patients with tuberculous pleurisy was also much higher than that of pleural effusion (P < 0.01). And there was no correlation between E-selectin of serum and that of pleural effusion in patients with tuberculous pleurisy (r = 0.16, P > 0.05).
CONCLUSION: E-selectin of serum and pleural effusion in patients with tuberculous pleurisy is produced from different sources. And E-selectin in patients with tuberculous pleurisy is much higher than those with lung cancer. Thence detecting E-selectin of serum and pleural effusion might be helpful for differentiating benign and malignant diseases.
METHOD: E-selectin of serum and pleural effusion in 23 patients with tuberculous pleurisy and 21 patients with lung cancer involving pleura was detected by ELISA method.
RESULT: E-selectin of serum(44 +/- 5 micrograms/L) and pleural effusion (24 +/- 3 micrograms/L) in patients with tuberculous pleurisy was much higher than that of serum (27 +/- 4 micrograms/L) and pleural effusion (11 +/- 3 micrograms/L) in lung cancer patients (P < 0.01). In addition, E-selection of serum in patients with tuberculous pleurisy was also much higher than that of pleural effusion (P < 0.01). And there was no correlation between E-selectin of serum and that of pleural effusion in patients with tuberculous pleurisy (r = 0.16, P > 0.05).
CONCLUSION: E-selectin of serum and pleural effusion in patients with tuberculous pleurisy is produced from different sources. And E-selectin in patients with tuberculous pleurisy is much higher than those with lung cancer. Thence detecting E-selectin of serum and pleural effusion might be helpful for differentiating benign and malignant diseases.