Penile Metastasis From Castration-Resistant Prostate Cancer: A Case Report.

INTRODUCTION

Penile metastasis from prostate cancer-generally associated with a poor prognosis-is rare and underreported. We report one relevant case.

CASE PRESENTATION: The patient was a 65-year-old male with metastatic hormone-sensitive prostate cancer (prostate-specific antigen [PSA]: 500 ng/mL) and lung, bone, and lymph node metastases. The patient received luteinizing hormone-releasing hormone agonist monotherapy. The patient developed castration-resistant prostate cancer and received androgen receptor signal inhibitor therapy and chemotherapy. As the disease progressed, a mass formed on his penis; biopsy revealed prostate cancer penile metastasis. The patient died 5 months later.

CONCLUSION

Penile metastasis is rare and typically observed in advanced prostate cancer stages. Awareness may aid in early recognition, guide palliative management, and support patient counseling.