Indian pediatrics · 2014
Multicystic dysplastic kidney: a retrospective study.
СтатьяНазвание и аннотация: Перевод в очереди
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Sharada Sathish, Vijayakumar Mahalingam, Nageswaran Prahlad, Ekambaram Sudha, Udani Amish
Аннотация
OBJECTIVE: To report the renal structural and functional anomalies in children with multicystic dysplastic kidneys.
METHODS: Retrospective descriptive analysis of 47 children with multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years.
RESULTS: Antenatal diagnosis of multicystic dysplastic kidney was made in 34 (72.3%) patients. On follow up of 31 children for more than 12 months, 21 (68%) had involution, 4 [13%] had non-regression, and 4 (13%) were nephrectomized. Vesico-ureteric reflux (n=13; 28%) was the commonest renal abnormality. The serum creatinine values were higher (P=0.006) in children with contralateral reflux. Sub-nephrotic proteinuria was noted in 9 (29%) and was significantly associated with complete involution (P=<0.023). None of the patients developed hypertension and 2 (6.4%) had renal failure.
CONCLUSIONS: Close nephrological follow-up is needed in children with multicystic dysplasia of kidneys.
METHODS: Retrospective descriptive analysis of 47 children with multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years.
RESULTS: Antenatal diagnosis of multicystic dysplastic kidney was made in 34 (72.3%) patients. On follow up of 31 children for more than 12 months, 21 (68%) had involution, 4 [13%] had non-regression, and 4 (13%) were nephrectomized. Vesico-ureteric reflux (n=13; 28%) was the commonest renal abnormality. The serum creatinine values were higher (P=0.006) in children with contralateral reflux. Sub-nephrotic proteinuria was noted in 9 (29%) and was significantly associated with complete involution (P=<0.023). None of the patients developed hypertension and 2 (6.4%) had renal failure.
CONCLUSIONS: Close nephrological follow-up is needed in children with multicystic dysplasia of kidneys.