Journal of acquired immune deficiency syndromes (1999) · 2026
PrEP and Contraceptive Persistence Among Young Women Receiving Sexual and Reproductive Health Services Through Hair Salons in South Africa.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Bassett Ingrid V, Yan Joyce, Govere Sabina, Johnson Lyra S, Shezi Sthabile, Ngcobo Lungile M, Sagar Shruti, Jarolimova Jana, Zionts Dani, Khumalo Anele, Zwane Pretty-Girl, Dube Nduduzo, Psaros Christina, Parker Robert A
Аннотация
BACKGROUND: Young women have high HIV incidence and risk for unintended births in sub-Saharan Africa. Hair salons may be useful settings for HIV prevention and family planning. We assessed PrEP and contraceptive persistence in South African hair salons.
METHODS: We conducted a pilot randomized trial to evaluate uptake and persistence of pre-exposure prophylaxis (PrEP) and contraception in 3 salons in KwaZulu-Natal. Women could start or stop medication at any visit. We defined persistence as 1 additional visit within 6 months with continued use. We assessed age, self-perceived HIV risk, partner 5 years older, primary partner having other partners, intimate partner violence, STI at enrolment, contraception persistence, mental health, and alcohol use using contingency tables.
RESULTS: Among 159 intervention participants, the median age was 26 years (IQR 22-29). Thirty-five (26%) were HIV positive, and 42/158 (27%) were using contraception at enrolment. 32/111 (29%) described at least moderate HIV risk in the following year, and 46/142 (32%) reported partners with other partners. 63/124 (51%) accepted PrEP; among 60 with follow-up data, 32 (53%) persisted. 138/159 (87%) took contraception; among 134 with follow-up data, 95 (71%) persisted. Persistence on PrEP was associated with age 25 and older (RR: 1.83 [95% CI: 1.03 to 4.00]), alcohol use (RR: 1.68 [95% CI: 1.03 to 2.92]), partner concurrency (RR: 0.49 [95% CI: 0.14 to 0.95]), and contraceptive persistence (RR: undefined).
CONCLUSIONS: Women accepted PrEP and contraception through hair salons, with contraception persistence higher than PrEP. PrEP persistence was associated with age, alcohol use, partner concurrency, and contraceptive persistence. Hair salons are a novel venue for service delivery.
METHODS: We conducted a pilot randomized trial to evaluate uptake and persistence of pre-exposure prophylaxis (PrEP) and contraception in 3 salons in KwaZulu-Natal. Women could start or stop medication at any visit. We defined persistence as 1 additional visit within 6 months with continued use. We assessed age, self-perceived HIV risk, partner 5 years older, primary partner having other partners, intimate partner violence, STI at enrolment, contraception persistence, mental health, and alcohol use using contingency tables.
RESULTS: Among 159 intervention participants, the median age was 26 years (IQR 22-29). Thirty-five (26%) were HIV positive, and 42/158 (27%) were using contraception at enrolment. 32/111 (29%) described at least moderate HIV risk in the following year, and 46/142 (32%) reported partners with other partners. 63/124 (51%) accepted PrEP; among 60 with follow-up data, 32 (53%) persisted. 138/159 (87%) took contraception; among 134 with follow-up data, 95 (71%) persisted. Persistence on PrEP was associated with age 25 and older (RR: 1.83 [95% CI: 1.03 to 4.00]), alcohol use (RR: 1.68 [95% CI: 1.03 to 2.92]), partner concurrency (RR: 0.49 [95% CI: 0.14 to 0.95]), and contraceptive persistence (RR: undefined).
CONCLUSIONS: Women accepted PrEP and contraception through hair salons, with contraception persistence higher than PrEP. PrEP persistence was associated with age, alcohol use, partner concurrency, and contraceptive persistence. Hair salons are a novel venue for service delivery.