The Effectiveness of Live Birth Rate of Traditional Chinese Medicine Intervention for Infertile Women Undergoing a Second Round of IVF Is Influenced by Age.

BACKGROUND/AIM: While in vitro fertilization (IVF) is an effective treatment for infertility, the live birth rate remains suboptimal. This study aimed to evaluate the factors influencing live birth rates in infertile women undergoing a second round of IVF combined with traditional Chinese medicine (TCM) treatment.

PATIENTS AND

METHODS

This was a single-center, retrospective cohort study involving 45 infertile women undergoing a second round of IVF who underwent a combined treatment approach integrating TCM with IVF. Clinical factors affecting live birth rates were analyzed using Student's t test, Pearson's Chi-square test, and univariate logistic regression models.

RESULTS

The findings revealed a clinical pregnancy rate of 51.11% and a live birth rate of 42.22%, underscoring the potential effectiveness of combining TCM with a second round of IVF for infertile women. Additionally, maternal age showed a statistically significant influence on the clinical pregnancy rate (39.32±2.93 years vs. 36.48±2.47 years, p=0.005) and live birth rate (39.68±2.85 years vs. 35.58±2.95 years, p<0.001).

CONCLUSION

Integrating traditional Chinese medicine into IVF protocols notably enhances maternal success rates. For women over 38, age-specific strategies such as fertility preservation, optimized ovarian stimulation, advanced embryo selection, and oocyte donation are key to addressing age-related challenges.