Frontiers in pediatrics · 2026
Recurrence rate and risk factors of recurrence after antiseizure medications withdrawal in children with epilepsy: a meta-analysis.
СтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lv Hechengyue, Wang Rui, He Yueyue, Wen Nan, Ouyang Weixiu, Peng Jianyu, Jiang Qian, Zhang Junli, Feng Ling
Аннотация
OBJECTIVE: This study aims to explore the recurrence rate and risk factors for recurrence after antiseizure medications withdrawal in children with epilepsy through a meta-analysis.
METHODS: Databases were searched up to May 8, 2025. Two reviewers independently screened the literature, extracted data, and assessed study quality. A meta-analysis was performed using Stata 15.0.
RESULTS: Nineteen studies involving 3,226 children were included. The pooled recurrence rate was 28% (95% CI: 23%-33%). Risk factors included female gender, focal seizure, history of febrile seizures, delayed development/intellectual disability, symptomatic etiology, abnormal electroencephalogram (EEG) after withdrawal.
CONCLUSION: Multiple factors increase recurrence risk after antiseizure medications withdrawal in children, supporting individualized clinical decision-making.
METHODS: Databases were searched up to May 8, 2025. Two reviewers independently screened the literature, extracted data, and assessed study quality. A meta-analysis was performed using Stata 15.0.
RESULTS: Nineteen studies involving 3,226 children were included. The pooled recurrence rate was 28% (95% CI: 23%-33%). Risk factors included female gender, focal seizure, history of febrile seizures, delayed development/intellectual disability, symptomatic etiology, abnormal electroencephalogram (EEG) after withdrawal.
CONCLUSION: Multiple factors increase recurrence risk after antiseizure medications withdrawal in children, supporting individualized clinical decision-making.