[Pathomorphological features of placentas with the single umbilical artery and a study of follow-ups of these babies].

The paper deals with the evaluation of pathomorphological and morphometrical changes in placenta with the single umbilical artery (SUA). The histological data on 52 placentas with SUA (group 1) were analyzed. A control group included 30 placentas from females with an uncomplicated obstetrical history. The significance of group differences was determined Student's test. In the placentas with SUA, their pathohistology shows a significantly marked isolated placental form of chronic placental insufficiency. In SUA, chorionic villous maturation and differentiation are impaired. Chorionic villous immaturity hampers the development of adequate compensatory adaptive changes that appear as compensatory angiomatosis of terminal villi and more pronounced cytotrophoblastic microcystic changes.