[Mitotic regime of benign and malignant tumors of the trophoblast].

Mitotic regimen was studied in 52 choriocarcinomas and 45 hydatidiform moles. A clear-cut correlation between the rate of proliferation and degree of hyperplasia of the trophoblast was established for hydatidiform mole. Choriocarcinoma revealed higher values for mitotic index, incidence of pathologic mitoses and the profile of abnormal cell division patterns. Higher mitotic index and incidence of pathologic mitoses in cases of choriocarcinoma were associated with less favorable clinical course of the disease. The presence of villi ruled out the diagnosis of choriocarcinoma.