Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology · 2002
[Neuropathologic investigation of area tempestas sclerosis in epileptic sensitive rats].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Du Xin-Lu, Zhao Jie, Zhang Wan-Qin
Аннотация
AIM AND METHODS: The relation between AT sclerosis (loss of neurons and proliferation of astrocytes) and long-lasting epileptic susceptibility was investigated by thionine staining, GFAP immunohistochemistry and observing the behavior of rats, after scorpion venom (SV) or normal saline (NS) administrated for three week.
RESULTS: Compared with NS+ NS group, both the loss of neurons and proliferation of astrocytes were very marked in KA+ NS group (epileptic susceptible rats) (P < 0.05), but those changes were not visible in KA+ NS group (epileptic nonsusceptible rats).
CONCLUSIONS: It suggested that AT sclerosis may be one of important reasons of the long-lasting epileptic susceptibility.
RESULTS: Compared with NS+ NS group, both the loss of neurons and proliferation of astrocytes were very marked in KA+ NS group (epileptic susceptible rats) (P < 0.05), but those changes were not visible in KA+ NS group (epileptic nonsusceptible rats).
CONCLUSIONS: It suggested that AT sclerosis may be one of important reasons of the long-lasting epileptic susceptibility.