Acta obstetricia et gynecologica Scandinavica · 1996
Plasma lipids, lipoproteins and apolipoproteins in hirsute women.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Castelo-Branco C, Casals E, Martinez de Osaba M J, Sanllehy C, Fortuny A
Аннотация
OBJECTIVE: To determine whether lipid alterations in hirsute women are due to excessive androgen, low estrogen or to a combination of these abnormalities.
DESIGN: Cross sectional study.
PATIENTS: Forty-five hirsute women between 15 and 39 years of age.
MAIN OUTCOME MEASURES: FSH, LH, 17beta-estradiol, PRL, testosterone, androstenedione, triglycerides and apolipoproteins A-I and B.
RESULTS: Testosterone was correlated with triglycerides (r: 0.76, p<0.01), HDL (r: -0.61, P<0.01) and LDL (r: 0.50, p<0.05). Both HDL (r: 0.66, p<0.01) and LDL (r: -0.57, p<0.01) were correlated with estradiol. Total cholesterol was also correlated with estradiol (r: -0.52, p<0.05). Cross adjusted correlations revealed that, after adjusting for estradiol, lipids were associated with testosterone and that estradiol was also correlated with lipids when adjusted for testosterone.
CONCLUSION: The results suggest that altered lipids in women with hyperandrogenism could result from independent effects of androgens and estrogens.
DESIGN: Cross sectional study.
PATIENTS: Forty-five hirsute women between 15 and 39 years of age.
MAIN OUTCOME MEASURES: FSH, LH, 17beta-estradiol, PRL, testosterone, androstenedione, triglycerides and apolipoproteins A-I and B.
RESULTS: Testosterone was correlated with triglycerides (r: 0.76, p<0.01), HDL (r: -0.61, P<0.01) and LDL (r: 0.50, p<0.05). Both HDL (r: 0.66, p<0.01) and LDL (r: -0.57, p<0.01) were correlated with estradiol. Total cholesterol was also correlated with estradiol (r: -0.52, p<0.05). Cross adjusted correlations revealed that, after adjusting for estradiol, lipids were associated with testosterone and that estradiol was also correlated with lipids when adjusted for testosterone.
CONCLUSION: The results suggest that altered lipids in women with hyperandrogenism could result from independent effects of androgens and estrogens.