Safety and efficacy of same-day discharge after gastric peroral endoscopic myotomy for gastroparesis: a systematic review and meta-analysis.

BACKGROUND AND AIMS: Postoperative care after gastric peroral endoscopic myotomy (G-POEM) in refractory gastroparesis lacks standardization. In this meta-analysis, we have evaluated the readmission rate, emergency department (ED) visits, and procedure-related adverse events between same-day discharge (SDD) versus overnight admission for observation after G-POEM.

METHODS

We reviewed several databases from inception to July 14, 2025. Outcomes of interest were readmissions, ED visits, procedure-related adverse events, and the mean procedure time. Data were analyzed using a random effects model.

RESULTS

There was no significant difference in readmission rate (risk ratio [RR], 0.93; 95% CI, 0.29-3.00), ED visits (RR, 0.88; 95% CI, 0.09-8.52), and procedure-related adverse events (RR, 0.53; 95% CI, 0.17-1.65) between the SDD and overnight admission groups. Procedure time was significantly shorter in the SDD group (mean difference, -9.61; 95% CI, -14.57 to -4.66).

CONCLUSIONS

This meta-analysis demonstrates no significant difference in outcomes between patients with same-day discharge versus overnight admissions after G-POEM.