Revista de salud publica (Bogota, Colombia) · 2018
[Urban outbreak of leishmaniasis in Colombia].
СтатьяНазвание и аннотация: Перевод в очереди
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Manotas-Berdugo Hernán, Toro-Maldonado Jessica, Rodríguez-Rodríguez Jairo, Salgado-García Doris
Аннотация
OBJECTIVES: To describe the epidemiology, clinical characteristics and treatment of children with visceral Leishmaniasis in Neiva- Huila, from April to June 2012.
METHODOLOGY: We performed a descriptive study of an outbreak of visceral leshmaniasis in children from the urban area of Neiva.
RESULTS: There were seven cases in children younger than five years. All of them had prolonged fever, hepato-splenomegaly, severe anemia and leukopenia. Five were admitted with severe thrombocytopenia, without hemorrhagic manifestations. Six patients received first-line treatment with miltefosine, five of them had treatment failure requirirng therapy escalation to amphotericin B, two received liposomal amphotericin B and three deoxycholate amphotericin B. The main vector identified was the Lutzomyia gomezi and its main reservoir were canines.
CONCLUSION: We describe the first visceral leishmaniasis outbreak in children living in an urban area, with no mortality. Most of the cases had a good response to amphotericin B.
METHODOLOGY: We performed a descriptive study of an outbreak of visceral leshmaniasis in children from the urban area of Neiva.
RESULTS: There were seven cases in children younger than five years. All of them had prolonged fever, hepato-splenomegaly, severe anemia and leukopenia. Five were admitted with severe thrombocytopenia, without hemorrhagic manifestations. Six patients received first-line treatment with miltefosine, five of them had treatment failure requirirng therapy escalation to amphotericin B, two received liposomal amphotericin B and three deoxycholate amphotericin B. The main vector identified was the Lutzomyia gomezi and its main reservoir were canines.
CONCLUSION: We describe the first visceral leishmaniasis outbreak in children living in an urban area, with no mortality. Most of the cases had a good response to amphotericin B.