Biochemical medicine and metabolic biology · 1992
The effect of drug exposure on thyroid hormone levels of newborns.
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Hernandez J T, Hoffman L, Weavil S, Cvejin S, Prange A J
Аннотация
This study examines the effect of women's alcohol abuse during pregnancy on the thyroid-stimulating hormone (TSH) and thyroxine (T4) levels of their babies at birth. Forty-seven babies were born to mothers identified as substance abusers. Maternal use of marijuana and/or cocaine did not result in newborns' TSH and T4 hormone levels being significantly different from non-substance-abusing controls' TSH and T4 levels. Alcohol use, however, was significantly linked to lower newborn TSH levels, lower than TSH levels of a control sample of newborns whose mothers used marijuana and/or cocaine, and lower than a control sample of newborns whose mothers abused no substances. This finding suggests further investigation of possible links between thyroid functioning and fetal alcohol syndrome (FAS).