Effect of radiophosphorus on chromosomes in swiss albino mice during postnatal development.

Swiss albino mice of one to five weeks of age were injected with P-32 at the dose of 1 muCi/g body weight and were autopsied when they were six weeks old. Karyological examination was carried out on bone-marrow cells. The chromosome aberrations observed were terminal and interstitial deletions, dicentrics, metacentrics, and rings. The frequency of aneuploid cells observed was 1.4%.