Internal medicine (Tokyo, Japan) · 2016
Cases with Refractory Ascites and a Delayed Response to Tolvaptan.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Hagiwara Satoru, Nishida Naoshi, Chishina Hirokazu, Ida Hiroshi, Sakurai Toshiharu, Komeda Yoriaki, Kitano Masayuki, Kudo Masatoshi
Аннотация
The patient was a 67-year-old female with liver cirrhosis due to hepatitis C. She was administered furosemide at 20 mg/day and spironolactone at 25 mg/day, but the ascites did not improve. Despite the additional administration of tolvaptan at 3.75 mg/day, the response to ascites was still poor. While the dose of tolvaptan was thereafter increased to 7.5 mg/day on the 7th hospital day, the ascites still persisted. However, she continued to receive tolvaptan (7.5 mg/day) because the worsening of her subjective symptoms was mild and she wished to do so. The ascites was later found to have almost completely disappeared on computed tomography (CT) at 6 months.