Long-term Experience and Visual Acuity Outcomes in Patients With Peters Anomaly.

PURPOSE: To report the results from a cases series of patients with Peters anomaly and propose management and treatment approaches according to the alterations associated with each case.

METHODS

The records of 27 patients (32 eyes) clinically diagnosed as having Peters anomaly were analyzed retrospectively. Each patient underwent different treatment modalities (from medical follow-up consultations to penetrating keratoplasty procedures) according to the type of Peters anomaly.1

Results

Of 32 eyes of 27 patients (74% male and 26% female), 5 patients (18.5%) were bilateral and 22 (81.5%) were unilateral. The average number of years of follow-up consultations was 10.2 years (range: 3.5 to 18 years). The long-term visual acuity (VA) results correlated directly with the type of Peters anomaly. Mean VA for all patients was 1.71 ± 1.04 logarithm of the minimum angle of resolution (logMAR). The results by group were 0.30 ± 0.00 logMAR for type I Peters anomaly with only medical monitoring, 0.97 ± 0.78 logMAR for type I Peters anomaly with only optical iridectomy, 1.22 ± 0.97 logMAR for type I Peters anomaly with penetrating keratoplasty, 2.41 ± 0.80 logMAR for type II Peters anomaly without a compromised posterior pole with penetrating keratoplasty, and 2.56 ± 0.48 logMAR for type II Peters anomaly with a compromised posterior pole with penetrating keratoplasty.

CONCLUSIONS

The VA result and long-term corneal failure is directly related to the type of Peters anomaly. Patients with type I Peters anomaly who only required medical follow-up consultations had the most favorable prognosis. Patients in whom penetrating keratoplasty was performed had a poor prognosis. [J Pediatr Ophthalmol Strabismus. 2021;58(5):304-310.].