Endocrine, metabolic & immune disorders drug targets · 2014
Immunological aspects of metritis in dairy cows: a review.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Pantaleo Marianna, Rizzo Annalisa, D'Onghia Giovanni, D'Onghia Gianfranco, Roncetti Maria, Piccinno Mariagrazia, Mutinati Maddalena, Terlizzi Michele Roberto, Sciorsci Raffaele Luigi
Аннотация
This paper reviews puerperal metritis in the cow, particularly the complex and multi-factorial pathogenesis characterized by an altered cross-talk among infectious agents, endocrine and immune systems. Uterine infections impair fertility and is one of the main causes of economic losses in dairy production. The early postpartum is a period characterized by an increased exposition to infectious agents and the disruption of the metabolic homeostasis, leading to endocrine and immunologic disorders. Dysregulation of uterine defence mechanisms results in the development of metritis. Because there is a complex interaction between infectious, endocrine and immune factors during metritis, there is need to use safer and cheaper drugs which are able to strengthen the anti-infective actions of the routine therapies.