Hypospadias and Kallmann's syndrome: distinction between morphogenesis and growth of the male phallus.

Although some boys with hypospadias have a small phallus, few actually have micropenis. Boys with Kallmann's syndrome have an endocrinopathy and micropenis, yet the disease is not associated with hypospadias. We present a boy affected by both Kallmann's syndrome and hypospadias. One might assume a closer association of these two diseases, as they both are hormonally dependent and severely affect the genitalia. In actuality, the coexistence of the two disorders has not been previously reported. This rare association provides the opportunity to consider how the morphogenesis and growth of the male phallus are temporally and hormonally distinct.