Acute phase of drug withdrawal management by clothiapine (Entumin): a pilot project.

Fifty-nine drug addicts and alcoholics were treated with clothiapine for a period up to 2 months for alleviation of their withdrawal symptoms. Most of the patients cooperated with the treatment, and this was due to the very few side effects that were experienced by them. The patients were completely withdrawn from physical dependence on drugs and we were able to discharge them without an irresistible impulse for the drug.