Conjunctival myxoma, Zollinger-Ellison syndrome and abnormal thickening of the inter-atrial septum: a case report and review of the literature.

PURPOSE: To report a 36-year-old man with a slowly growing painless bulbar conjunctival mass.

RESULTS

Following excision of the lesion, histological examination was performed and a diagnosis of myxoma was made. A cardiac echogram showed thickening of the interatrial septum. Seventeen years previously he had had Zollinger Ellison syndrome due to gastrinoma of the pancreas which was treated by surgical removal. A review of the literature shows ocular myxomas may be associated with endocrine abnormalities such as Cushing's syndrome, acromegaly, sexual precocity and cardiac myxoma.

CONCLUSION

In this case we report a novel association of conjunctival myxoma with Zollinger-Ellison syndrome and inter-atrial septal thickening.