Syndromes of hydatidiform moles. Partial vs. complete.

Comparative cytogenetic studies of hydatidiform moles delineated two separate syndromes, the classic complete mole with a diploid karyotype and the partial mole with 69 chromosomes. The two syndromes are pathologically distinct, and although they have morphologic resemblances, they differ in their biology, and no transition between them is possible. In contrast to the complete mole, no choriocarcinoma has been found in association with the partial mole.