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DOI 10.1016/j.tripleo.2008.03.030

Медицинская библиотека · Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics · 2008

Reaction of rat connective tissue to a new calcium hydroxide-based sealer.

Gomes-Filho João Eduardo, Bernabé Pedro Felício Estrada, Nery Mauro Juvenal, Otoboni-Filho José Arlindo, Dezan-Júnior Eloi, de Moraes Costa Mariana Machado Teixeira, de Faria Max Douglas, Watanabe Simone, Gomes Alessandra Cristina

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Аннотация

The aim of this study was to histopathologically examine the reaction of the connective tissue of rats to 2 calcium hydroxide-based sealers, Acroseal and Sealapex. Dentin tubes containing the materials and empty control tubes were implanted into the dorsal connective tissue of 36 Wistar albino rats. The animals were killed after 7 or 30 days, and the specimens were prepared for histologic analysis with hematoxylin and eosin, Von Kossa technique, and polarized light. Results were statistically analyzed using Kruskal-Wallis test. Both materials caused mild or moderate inflammatory reactions on the 7th day, but these reactions decreased by the 30th day with no significant difference at any time (P > .05). Mineralization of the subcutaneous tissue of the rats was observed only with Sealapex.

Для цитирования: Gomes-Filho João Eduardo, Bernabé Pedro Felício Estrada, Nery Mauro Juvenal, Otoboni-Filho José Arlindo, Dezan-Júnior Eloi, de Moraes Costa Mariana Machado Teixeira, de Faria Max Douglas, Watanabe Simone, Gomes Alessandra Cristina. Reaction of rat connective tissue to a new calcium hydroxide-based sealer.. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2008. DOI: 10.1016/j.tripleo.2008.03.030.

Предметные рубрики MeSH

AnimalsBiocompatible MaterialsCalcium HydroxideConnective TissueDentinDermatitisHumansLymphocytesMacrophagesMaleMaterials TestingNecrosisNeutrophilsOssification, HeterotopicPlasma CellsRandom AllocationRatsRats, WistarRoot Canal Filling MaterialsSalicylatesSkinTime Factors
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