[Significance of biochemical parameters of saliva in the diagnosis of chronic obstructive pulmonary disease at exacerbation].

The levels of calcium, magnesium and iron were examined on an automated biochemical analyzer in saliva and blood serum of 102 patients with chronic obstructive disease of lungs (CODL) and of 20 healthy subjects. Reliably reduced levels of magnesium and iron in saliva as well as low permeability of the hematosalivary barrier (HSB) for magnesium and its high permeability for iron were detected in group 2 and 3 of patients. The dynamic level of iron in saliva reached the normal value, whereas, a stable salivary deficiency was typical of magnesium. The above tests of levels of magnesium and iron in saliva and the determination of the distribution factor for the above cations can be used in evaluating a severity of bronchial obstruction and therapy efficiency in patients with CODL.