[Placental production of growth factors and its value in the prediction of neonatal cerebral lesions].

The placental production of growth factors (epidermal growth factors (EGF) and placental growth factor (PGF)) was studied in females with complicated pregnancy. Analysis of the findings permitted calculation of an EGF/PGF ratio. This ratio was correlated with the babies' health status at birth and during neonatality. The clinical application of the EGF/PGF ratio makes it possible to predict neurological disorders in infants, to optimize therapeutic measures, to form groups at high risk for cerebral lesions, and to perform their timely correction.