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DOI 10.4103/jpbs.jpbs_288_25

Медицинская библиотека · Journal of pharmacy & bioallied sciences · 2025

Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines.

Thoke Gaurav Makrand, Sinduja Palati, Kaliaperumal Kumaravel, Gandham Swati, Rajasekar Subhashri, Murugesan Pavithra

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Аннотация

INTRODUCTION

Cancer continues to pose a significant challenge in the field of medicine, demanding innovative approaches and novel therapeutic avenues for effective treatment. Within this landscape, the exploration of natural compounds derived from marine organisms has garnered attention for their potential anti-cancer properties.

AIM: Our present study aims to evaluate the pharmacological effect of Aplidium species in terms of anti-cancer properties which are assessed through biochemical methods.

MATERIALS AND

METHODS

The sample was collected from the Thiruchender coastal areas. It was then washed and extracted with methanol which then was used for biological screening against two cancer strains, namely, MCF-7 (Breast cancer cell line) and A2780 (Ovarian Cancer cell line).

CONCLUSION

Alpidium sp extract has significant anticancer effect against two different cancer cell lines when compared to standard drugs.

Для цитирования: Thoke Gaurav Makrand, Sinduja Palati, Kaliaperumal Kumaravel, Gandham Swati, Rajasekar Subhashri, Murugesan Pavithra. Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines.. Journal of pharmacy & bioallied sciences. 2025. DOI: 10.4103/jpbs.jpbs_288_25.
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