Medicine · 2020
Acute encephalopathy with biphasic seizures and late reduced diffusion: A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Ma Yan-Li, Xu Kai-Li, Chen Guo-Hong, Wang Li, Wang Yuan, Jin Zhi-Peng
Аннотация
RATIONALE: Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) has been reported almost exclusively in the Japanese population.
PATIENT CONCERNS: A 17-month-old male patient presented with fever and seizures, and subsequently fell into a coma. On the second day, he recovered consciousness. On the fourth day, he developed complex partial seizures and fell into a coma again. On day 10, the fever and seizures subsided. Head computed tomography on the first day showed no abnormalities. Brain diffusion-weighted images on the fourth day revealed reduced diffusion in the bilateral subcortical white matter.
DIAGNOSIS: A diagnosis of AESD was made.
INTERVENTIONS: The patient was treated with corticosteroids and intravenous immunoglobulin.
OUTCOMES: At the 4-month follow-up, the patient was able to walk independently, and the epileptic seizures were well controlled.
LESSONS: AESD is a rare entity, and treatment with corticosteroids and intravenous immunoglobulin can lead to a favorable prognosis. Clinicians should be aware of this condition, and clinicoradiological features can suggest the diagnosis.
PATIENT CONCERNS: A 17-month-old male patient presented with fever and seizures, and subsequently fell into a coma. On the second day, he recovered consciousness. On the fourth day, he developed complex partial seizures and fell into a coma again. On day 10, the fever and seizures subsided. Head computed tomography on the first day showed no abnormalities. Brain diffusion-weighted images on the fourth day revealed reduced diffusion in the bilateral subcortical white matter.
DIAGNOSIS: A diagnosis of AESD was made.
INTERVENTIONS: The patient was treated with corticosteroids and intravenous immunoglobulin.
OUTCOMES: At the 4-month follow-up, the patient was able to walk independently, and the epileptic seizures were well controlled.
LESSONS: AESD is a rare entity, and treatment with corticosteroids and intravenous immunoglobulin can lead to a favorable prognosis. Clinicians should be aware of this condition, and clinicoradiological features can suggest the diagnosis.