A clinico-pathological study of the role of allergy on larynx in children.

Laryngeal manifestation of allergy though less common than rhinosinusitis, tubotympanitis and bronchopulmonary allergy is not that uncommon and is usually misdiagnosed and mistreated in children. Hence, the importance of larynx as the allergic shock organ in children with spasmodic croup and laryngotracheo hronchits. In the present study, children below five years, presenting with Stridor and/or hoarseness were evaluated regarding the history of allergy, direct laryngoscopic finding, measurement of serum IgE,. presence of eosinophilia and histopathological examination of laryngeal biopsy. Out of the 80 cases studied, 9 cases (11.2%) presented with associated allergic manifestation, 8 cases (10%) having family history of allergy. 4 cases (5%) having raised serum lgE, 12 cases (15%) with eosinophilia and 3 cases (3.75%) with eosinophilic infiltration on histopathological examination of the biopsy material taken during the direct laryngoscopy.