Graphene oxide functionalized tannic acid-trimethylolpropane triglycidyl ether nanoparticles: a versatile network nanocatalyst for synthesis of 4-substituted-1,5-benzodiazepine derivatives.

This work is described through a one-pot three-component reaction of o-phenylenediamine, and dimedone, under reflux conditions in aqueous ethanol/H2O (1 : 1 v/v, 5 mL) in the presence of GO@tannic acid-TTE. The main advantages of this method are the ease of operation, purification, and the absence of hazardous and expensive solvents and catalysts. Also, this catalyst has the ability to perform this reaction in large quantities on an industrial scale. FT-IR, TGA, XRD, EDX, elemental mapping, TEM, and SEM methods have been used to characterize the prepared nanocatalyst. The catalyst can be reused several times.