Inappropriate secretion of antidiuretic hormone (SIADH) in a patient with pleurisy related to adult onset Still's disease.

The syndrome of inappropriate secretion of antidiuretic hormone (ADH) or SIADH has been so far reported in various disorders. However, to our knowledge, no case of SIADH associated with adult onset Still's disease (AOSD) has been described in the literature. We report on a patient who developed inappropriate secretion of antidiuretic hormone (SIADH) during the course of adult onset Still's disease (AOSD). The patient developed SIADH associated with pleuritis and improved when pleuritis subsided during the course of steroid therapy. Thus, it seems suggest that SIADH was induced by AOSD which is considered to be related with vasculitis.