Nonopioid analgesics.

Nonopioid analgesics represent a varied collection of analgesic agents, many of which also possess antipyretic or anti-inflammatory actions. As a group, nonopioid analgesics represent reasonable first-line analgesics for a variety of mild to moderate painful conditions and also often may be useful in conjunction with other analgesics (eg, opioids) for a myriad of severe painful conditions. Clinicians treating pain should be familiar with the actions, adverse effects, and individual agents in the group of nonopioid analgesics.