Simulating moxalactam dosage for extended-spectrum β-lactamase-producing Enterobacteriaceae using blood antimicrobial surveillance network data.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ortinau Cynthia M, Wypij David, Ilardi Dawn, Rofeberg Valerie, Miller Thomas A, Donohue Janet, Reichle Garrett, Seed Mike, Elhoff Justin, Alexander Nneka, Allen Kiona, Anton Corinne, Bear Laurel, Boucher Gina, Bragg Jennifer, Butcher Jennifer, Chen Victoria, Glotzbach Kristi, Hampton Lyla, Lee Caroline K, Ly Linh G, Marino Bradley S, Martinez-Fernandez Yadira, Monteiro Sonia, Ortega Christina, Peyvandi Shabnam, Raiees-Dana Heather, Rollins Caitlin K, Sadhwani Anjali, Sananes Renee, Sanz Jacqueline H, Schultz Amy H, Sood Erica, Tan Alexander, Willen Elizabeth, Wolfe Kelly R, Goldberg Caren S
Аннотация
METHODS: This is a retrospective cohort study of children born between September 2017 and September 2018 who underwent cardiopulmonary bypass in their first year of life at a center contributing data to the Cardiac Neurodevelopmental Outcome Collaborative and Pediatric Cardiac Critical Care Consortium clinical registries. The primary outcome was attendance for a neurodevelopmental evaluation between 11 and 30 months of age. Sociodemographic and medical characteristics and center factors specific to neurodevelopmental program design were considered as predictors for attendance.
RESULTS: Among 2385 patients eligible from 16 cardiac centers, the attendance rate was 29.0% (692 of 2385), with a range of 7.8% to 54.3% across individual centers. In multivariable logistic regression models, hospital-initiated (versus family-initiated) scheduling for neurodevelopmental evaluation had the largest odds ratio in predicting attendance (odds ratio = 4.24, 95% confidence interval, 2.74-6.55). Other predictors of attendance included antenatal diagnosis, absence of Trisomy 21, higher Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery mortality category, longer postoperative length of stay, private insurance, and residing a shorter distance from the hospital.
CONCLUSIONS: Attendance rates reflect some improvement but remain low. Changes to program infrastructure and design and minimizing barriers affecting access to care are essential components for improving neurodevelopmental care and outcomes for children with congenital heart disease.