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DOI 10.1055/s-0040-1705135

Медицинская библиотека · American journal of perinatology · 2020

Umbilical Cord Blood Lead Level Disparities between Flint and Detroit.

Hanna-Attisha Mona, Gonuguntla Ashweena, Peart Nadine, LaChance Jenny, Taylor D Kay, Chawla Sanjay

Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVE

The lead-in-water impact of the Flint water crisis on the youngest and most neurodevelopmentally vulnerable population was largely unknown. The objective of this study was to investigate and compare cord blood lead levels (CBLLs) in newborns in Flint, Michigan, after the Flint water crisis, to a group of Detroit newborns.

STUDY

DESIGN

Mothers of 99 Flint newborns were surveyed about potential lead exposures. These neonates were born after the recognition of population-wide lead-in-water contamination. CBLLs were measured and maternal-fetal metrics were reviewed. CBLLs and maternal-fetal metrics were then compared with those of a retrospective cohort of 116 Detroit newborns who previously shared the same water source. Analysis involved descriptive statistics, independent t-test, and χ 2 analysis.

RESULTS

CBLLs greater than or equal to 1 μg/dL (0.05 μmol/L) were more prevalent among Flint newborns (14%), as compared with Detroit newborns (2%; p = 0.001). This was a sevenfold disparity between Flint and Detroit newborns. No statistically significant differences were found in birth weight, head circumference, small for gestational age status, gestational age, or preterm status among the two groups.

CONCLUSION

The Flint water crisis potentially exposed newborns to lead in utero, implicating maternal-fetal outcomes and future health and development. Primary prevention efforts, including identification and mitigation of lead exposure before conception and during pregnancy, are needed. New environmental exposure detection methods and long-term neurodevelopmental follow-up will complement the findings of this study.

Для цитирования: Hanna-Attisha Mona, Gonuguntla Ashweena, Peart Nadine, LaChance Jenny, Taylor D Kay, Chawla Sanjay. Umbilical Cord Blood Lead Level Disparities between Flint and Detroit.. American journal of perinatology. 2020. DOI: 10.1055/s-0040-1705135.

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