Phase similarity between similar objects indicates representational merging across retrieval training but not sleep.

Retrieval training (i.e., cued recall) is theorised to induce rapid memory consolidation, similarly to sleep. Across consolidation, related neural representations become increasingly similar; yet, representational change has never been directly compared between sleep and retrieval training to test similarities in their underlying mechanisms. In this study, 30 subjects (27F, 18-34, M = 22.17) completed 4 separate sessions in which they (1) learnt object-word pairs, followed by (2) immediate recognition testing, (3) one of four 120-min interventions (retrieval training, restudy, sleep, or wake), and (4) delayed recognition testing. We compared EEG phase similarity between similar and different objects to assess the time, frequency, and anatomical distribution of representational similarity across encoding (learning to immediate recognition), and each intervention (immediate to delayed recognition). We hypothesised that EEG phase patterns for similar objects would become more similar (i.e., representational merging) across retrieval training and sleep interventions, and predict a greater endorsement of similar-object lures. We found increased representational similarity between similar objects across encoding in the theta-band and occipital sources. Crucially, additional representational merging was only observed across the retrieval training intervention, in the alpha-band and parieto-occipital sources. Despite retrieval training leading to reduced performance in discriminating similar-objects lures, greater representational merging across retrieval training predicted greater discrimination of similar-object lures. Together, these findings suggest that sleep and retrieval training induce different memory transformations across equivalent timescales. Retrieval training may generally provoke rapid gist extraction, with greater neocortical integration supporting episodic discrimination. Conversely, sleep may selectively maintain short-term task-relevant episodic and semantic details.