Fetus with features of Crane-Heise syndrome and aminopterin syndrome sine aminopterin (ASSAS).

A male fetus with multiple congenital abnormalities is reported. The parents of the fetus are consanguineous. There were unusual facial features, digital anomalies, cleft palate, a malformed tongue that prevented swallowing, absent clavicles and genital hypoplasia. The fetus had features suggestive of both Crane-Heise syndrome and aminopterin syndrome sine aminopterin (ASSAS), and may represent part of a spectrum of abnormalities including these conditions.