The Journal of veterinary medical science · 2023
Pleural mesothelioma in a California sea lion (Zalophus californianus).
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Takami Yuki, Tanaka Miyuu, Morita Masahiro, Maruno Takaya, Anai Naohiro, Sudo Tsubasa, Kezuka Chiho, Izawa Takeshi, Yamate Jyoji, Kuwamura Mitsuru
Аннотация
A 25-year-old female California sea lion (Zalophus californianus) reared in an aquarium died following a history of anorexia, lethargy, abnormal protrusion of the skin, and oral respiration. At necropsy, multiple yellowish-white nodules with diameters of 0.1-0.5 cm were disseminated in the thoracic cavity and lungs. Histopathologically, the nodules were continuous with normal mesothelium and were characterized by the proliferation of spindle-shaped to polygonal neoplastic cells with prominent atypia. The neoplastic cells exhibited diffuse, strong staining for vimentin and partial, weak to moderate staining for cytokeratin AE1/AE3. Based on these findings, the lesions were diagnosed as pleural mesothelioma. This study reports the first case of pleural mesothelioma in California sea lion.