Pan-urethral strictures can develop as a complication of UroLume placement for bulbar stricture disease in patients with hypospadias.

We report the development of pan-urethral strictures in 2 patients with hypospadias who underwent UroLume urethral stent placement for bulbar urethral stricture disease before referral to our institution. To our knowledge, this devastating complication has never previously been reported. The likely etiology was ischemic urethral stenosis secondary to occlusion of bulbar arteries, the dominant urethral blood supply in hypospadias patients who lack a secondary retrograde blood supply through the glans penis. We conclude that hypospadias should be an absolute contraindication to urethral stent placement.