Assessment of collagen hemostatic membrane and sponge in alveolar sockets: A quasi-experimental prospective clinical study.

BACKGROUND

This prospective split-mouth clinical study aimed to compare and evaluate bleeding, soft tissue healing, and pain management following tooth extractions using either the Lumina Coat® membrane or the Hemospon® sponge.

MATERIAL AND

METHODS

Thirty-two alveoli were included in this study. Following extraction, the sockets were filled with one of two materials: the Hemospon® collagen sponge (control group) or the Lumina Coat® collagen membrane (test group). Participants were assessed at 30 minutes, 24 hours and 48 hours postoperatively to evaluate bleeding, and were then recalled after 7 days for clinical assessment of soft tissue healing and suture removal. Soft tissue healing and bleeding were scored on a 0-3 scale, while pain was assessed using the visual analog scale (VAS). Data were expressed as means with standard deviations and analyzed using Prism 9 (GraphPad Software).

RESULTS

During the later postoperative period, pain scores decreased in both groups. Initial pain scores were 2.20 in the Lumina Coat group and 2.80 in the Hemospon group. By day 7, both groups reported an average score of 0.25 (p>0.05). Bleeding scores were elevated in both groups in the early postoperative phase. The Lumina Coat group had an average score of 1.35, compared with 1.65 in the Hemospon group. Scores decreased progressively over the first 24 hours, after which bleeding resolved completely. A statistically significant difference was observed at 30 minutes, with the Lumina Coat group showing lower scores (average 0.75) compared with the Hemospon group (average 1.20). Healing scores followed a similar pattern-higher in the immediate postoperative period but declining after 7 days. At 2 days postoperatively, the Lumina Coat group demonstrated significantly lower healing scores (average 0.35) than the Hemospon group (average 0.80).

CONCLUSIONS

Both materials were effective in controlling pain, reducing bleeding, and promoting soft tissue healing. However, the Lumina Coat group showed superior outcomes compared to Hemospon, particularly in reducing bleeding and improving healing scores.