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DOI 10.14639/0392-100x-a731

Медицинская библиотека · Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025

Impact of haemodialysis on vestibular function in adult patients with chronic kidney disease.

Viola Pasquale, De Luca Pietro, Scarpa Alfonso, Ricciardiello Filippo, Gioacchini Federico Maria, Anzivino Roberta, Barbara Francesco, Astorina Alessia, Zicarelli Mariateresa, Avallone Emilio, Coppolino Giuseppe, Andreucci Michele, Chiarella Giuseppe

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Аннотация

OBJECTIVE

Chronic kidney disease (CKD) is a global health problem with a significant impact on patients' quality of life. Haemodialysis, a common treatment for advanced CKD, can profoundly affect vestibular function, which plays a critical role in maintaining balance and spatial orientation.

METHODS

This prospective study was conducted over a 6-month period at the Magna Graecia University and included 18 adult patients with CKD stage 5, undergoing haemodialysis. Vestibular function was assessed using the Visual Analogue Scale (VAS) for the symptom of unsteadiness and the video Head Impulse Test (vHIT) for the vestibulo-ocular reflex (VOR) gain.

RESULTS

Our results showed a statistically significant decrease in VOR gain from 0.99 at T0 to 0.92 at T1 (T-test p = 0.034 and Welch Test p = 0.037), accompanied by an increase in VAS instability scores, after the dialysis session. These results suggest a worsening of vestibular function as a result of haemodialysis.

CONCLUSIONS

These results highlight the need for early diagnosis and timely intervention, such as vestibular rehabilitation, to reduce the risk of falls and improve the quality of life in CKD patients undergoing haemodialysis. Future research should investigate the long-term effects of haemodialysis on vestibular function.

Для цитирования: Viola Pasquale, De Luca Pietro, Scarpa Alfonso, Ricciardiello Filippo, Gioacchini Federico Maria, Anzivino Roberta, Barbara Francesco, Astorina Alessia, Zicarelli Mariateresa, Avallone Emilio, Coppolino Giuseppe, Andreucci Michele, Chiarella Giuseppe. Impact of haemodialysis on vestibular function in adult patients with chronic kidney disease.. Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale. 2025. DOI: 10.14639/0392-100x-a731.

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