Semergen · 2025
[Epidemiology, characteristics, and management of chronic kidney disease associated with diabetes in a health area of Cádiz].
СтатьяНаблюдательное исследованиеАннотация на английскомНазвание и аннотация: Перевод в очереди
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Escribano-Serrano J, Jiménez-Varo E, Escribano-Cobalea M, Casto-Jarillo C, López-Ceres A, Campos-Dávila E, Hormigo-Pozo A, Nieto-Ordoñez C, Rodríguez-Juliá M Á, Michán-Doña A
Аннотация
INTRODUCTION: Chronic Kidney Disease associated with Diabetes Mellitus (CKD-DM) is a prevalent condition with significant morbidity, mortality, and healthcare burden. Despite its relevance, its specific characteristics within the Spanish context have been scarcely described.
OBJECTIVE: To determine the prevalence, clinical phenotypes, and therapeutic management of CKD-DM according to KDIGO guidelines in a healthcare area in southern Spain.
METHODS: Observational, cross-sectional, and retrospective study based on SIDICAM records from July 2021 to June 2023 in the Campo de Gibraltar East Health Management Area. Diabetic patients (PDM) were identified and classified according to KDIGO 2024 criteria: estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR).
RESULTS: Among the 8,732 PDM analyzed, 32.3% had CKD-DM (95% CI: 31.3%-33.2%), and 6.9% met criteria for nephrology-range CKD-DM. The predominant phenotype was eGFR <60mL/min/1.73 m2 (14.2%), followed by the combined phenotype (9.2%) and isolated albuminuria (8.9%). Prevalence was higher in women and increased with age and diabetes duration. SGLT2 inhibitors were used in 48% of patients with CKD-DM, rising to 60% among the youngest group.
CONCLUSION: CKD-DM shows a high prevalence and phenotypic variability according to age, sex, and diabetes progression. This study highlights the need for personalized preventive and therapeutic strategies, as well as the crucial role that primary care must play in the early detection and management of CKD-DM.
OBJECTIVE: To determine the prevalence, clinical phenotypes, and therapeutic management of CKD-DM according to KDIGO guidelines in a healthcare area in southern Spain.
METHODS: Observational, cross-sectional, and retrospective study based on SIDICAM records from July 2021 to June 2023 in the Campo de Gibraltar East Health Management Area. Diabetic patients (PDM) were identified and classified according to KDIGO 2024 criteria: estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR).
RESULTS: Among the 8,732 PDM analyzed, 32.3% had CKD-DM (95% CI: 31.3%-33.2%), and 6.9% met criteria for nephrology-range CKD-DM. The predominant phenotype was eGFR <60mL/min/1.73 m2 (14.2%), followed by the combined phenotype (9.2%) and isolated albuminuria (8.9%). Prevalence was higher in women and increased with age and diabetes duration. SGLT2 inhibitors were used in 48% of patients with CKD-DM, rising to 60% among the youngest group.
CONCLUSION: CKD-DM shows a high prevalence and phenotypic variability according to age, sex, and diabetes progression. This study highlights the need for personalized preventive and therapeutic strategies, as well as the crucial role that primary care must play in the early detection and management of CKD-DM.
Предметные рубрики MeSH
HumansFemaleMaleRenal Insufficiency, ChronicCross-Sectional StudiesRetrospective StudiesMiddle AgedSpainAgedPrevalenceGlomerular Filtration RateAlbuminuriaSodium-Glucose Transporter 2 InhibitorsDiabetes MellitusDiabetic NephropathiesAdultPractice Guidelines as TopicPhenotypeSex FactorsAged, 80 and over