Nutrition reviews · 2022
Intergenerational high-fat diet impairs ovarian follicular development in rodents: a systematic review and meta-analysis.
СтатьяМетаанализПоддержка исследования: вне правительства СШАСистематический обзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Paula Verônyca G, Vesentini Giovana, Sinzato Yuri K, Moraes-Souza Rafaianne Q, Volpato Gustavo T, Damasceno Débora C
Аннотация
CONTEXT: Excessive consumption of high-fat diets has increased in the population over time and is harmful to female fertility.
OBJECTIVE: To investigate and discuss the effects of a high-fat diet on ovarian follicles in rodents.
DATA SOURCE: A systematic literature search of PubMed, EMBASE, Web of Science, and SCOPUS was carried out.
DATA EXTRACTION: Study characteristics, including study design, population, intervention, outcome, and risk of bias were analyzed.
DATA ANALYSIS: Twenty-two articles were included in a systematic review. Given the availability of studies, a quantitative meta-analysis included 12 studies that were performed for outcomes. There was a decrease in primordial follicles in female rodents that received a high-fat diet compared with the standard diet group. The offspring of mothers exposed to a high-fat diet showed an increased number of cystic follicles and a decreased number of secondary follicles and antral follicles, compared with the control diet group. Therefore, these high-fat diet-induced follicular alterations might impair the fertility of dams and their female newborns.
CONCLUSION: The consumption of a high-fat diet causes damage to ovarian follicular development, and this commitment will persist in the next generation.
SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration no. CRD42019133865.
OBJECTIVE: To investigate and discuss the effects of a high-fat diet on ovarian follicles in rodents.
DATA SOURCE: A systematic literature search of PubMed, EMBASE, Web of Science, and SCOPUS was carried out.
DATA EXTRACTION: Study characteristics, including study design, population, intervention, outcome, and risk of bias were analyzed.
DATA ANALYSIS: Twenty-two articles were included in a systematic review. Given the availability of studies, a quantitative meta-analysis included 12 studies that were performed for outcomes. There was a decrease in primordial follicles in female rodents that received a high-fat diet compared with the standard diet group. The offspring of mothers exposed to a high-fat diet showed an increased number of cystic follicles and a decreased number of secondary follicles and antral follicles, compared with the control diet group. Therefore, these high-fat diet-induced follicular alterations might impair the fertility of dams and their female newborns.
CONCLUSION: The consumption of a high-fat diet causes damage to ovarian follicular development, and this commitment will persist in the next generation.
SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration no. CRD42019133865.