Hysteroscopic findings in 344 women with recurrent spontaneous abortion.

STUDY

OBJECTIVE

To evaluate the prevalence of different anatomic factors in women with recurrent spontaneous abortion (RSA).

DESIGN

Retrospective analysis over 9 years (Canadian Task Force classification II-2).

SETTING

University hospital-affiliated endoscopic unit.

PATIENTS: Three hundred forty-four consecutive patients with RSA and 922 controls referred for abnormal uterine bleeding.

INTERVENTION: Diagnostic hysteroscopy.

MEASUREMENTS AND MAIN

RESULTS

Major and minor uterine mullerian abnormalities (septate, unicornuate uteri) were found significantly more often in women with RSA than in controls (32% vs 6%, p <0.001). The frequency of acquired uterine anomalies (submucous myomas, polyps) was significantly higher in controls (32% vs 9%, p <0.001). No significant differences were observed between groups in frequency of adhesions (4% vs 2%).

CONCLUSION

Major mullerian uterine abnormalities are associated with RSA, and minor uterine anomalies may be correlated with an increased risk of recurrent miscarriage.