Clinical neuropharmacology · 2016
Reversible Fluoxetine-Induced Hyperthyroidism: A Case Report.
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Lai Jianbo, Xu Dongrong, Peterson Bradley S, Xu Yi, Wei Ning, Zhang Minming, Hu Shaohua
Аннотация
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are typically used as antidepressants. Clinically significant SSRI-induced thyroid dysfunction is rare.
CASE: We report a case of hyperthyroidism induced by fluoxetine in a female patient with major depressive disorder. Her thyroid profiles indicated hyperthyroidism after a 10-week treatment with fluoxetine and were restored after discontinuation of fluoxetine and administration with venlafaxine. In the first year of follow-up, her thyroid functions as well as her depressive symptoms remained perfectly normal.
CONCLUSIONS: This case highlights the necessity of monitoring thyroid profiles during SSRI treatment.
CASE: We report a case of hyperthyroidism induced by fluoxetine in a female patient with major depressive disorder. Her thyroid profiles indicated hyperthyroidism after a 10-week treatment with fluoxetine and were restored after discontinuation of fluoxetine and administration with venlafaxine. In the first year of follow-up, her thyroid functions as well as her depressive symptoms remained perfectly normal.
CONCLUSIONS: This case highlights the necessity of monitoring thyroid profiles during SSRI treatment.