The Laryngoscope · 2015
Impact of patient-related factors on the outcomes of office-based injection laryngoplasty.
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Sardesai Maya G, Merati Albert L, Hu Amanda, Birkent Hakan
Аннотация
OBJECTIVES/HYPOTHESIS: In-office percutaneous injection laryngoplasty (IL) is a common treatment for glottal insufficiency. The objective of this prospective study was to determine if voice outcomes from IL are affected by age, gender, or initial disease severity.
STUDY DESIGN: Prospective case series.
METHODS: Consecutive adult patients undergoing awake injection laryngoplasty were recruited from a subspecialty laryngology clinic. Voice Handicap Index (VHI-30); Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V); and Grade, Roughness, Breathiness, Asthenia and Strain (GRBAS) Dysphonia Scale were evaluated prior to and 2 months after injection. Patients who had more severe disease were defined as those patients with greater initial perception of handicap, with a VHI score greater than 60.
RESULTS: Thirty-five subjects were enrolled, and 27 (16 male; mean age 61.6 ± 13.2 years) had complete data. No impact from age or gender was seen on outcomes from IL as measured by VHI-30 (P = 0.397 for age; P = 0.764 for gender), CAPE-V (P = 0.675 for age, P = 0.975 for gender), or GRBAS (P = 0.213 for age, P = 0.983 for gender). Patients with poorer initial VHI tended to have more significant improvement (P = 0.002), which may represent a ceiling effect.
CONCLUSIONS: In this prospective clinical study, age and gender did not affect outcome in IL. Patients with more severe disease appeared to have greater improvement.
LEVEL OF EVIDENCE: 4. Laryngoscope, 126:1806-1809, 2016.
STUDY DESIGN: Prospective case series.
METHODS: Consecutive adult patients undergoing awake injection laryngoplasty were recruited from a subspecialty laryngology clinic. Voice Handicap Index (VHI-30); Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V); and Grade, Roughness, Breathiness, Asthenia and Strain (GRBAS) Dysphonia Scale were evaluated prior to and 2 months after injection. Patients who had more severe disease were defined as those patients with greater initial perception of handicap, with a VHI score greater than 60.
RESULTS: Thirty-five subjects were enrolled, and 27 (16 male; mean age 61.6 ± 13.2 years) had complete data. No impact from age or gender was seen on outcomes from IL as measured by VHI-30 (P = 0.397 for age; P = 0.764 for gender), CAPE-V (P = 0.675 for age, P = 0.975 for gender), or GRBAS (P = 0.213 for age, P = 0.983 for gender). Patients with poorer initial VHI tended to have more significant improvement (P = 0.002), which may represent a ceiling effect.
CONCLUSIONS: In this prospective clinical study, age and gender did not affect outcome in IL. Patients with more severe disease appeared to have greater improvement.
LEVEL OF EVIDENCE: 4. Laryngoscope, 126:1806-1809, 2016.