Recurrence of Port-Wine Stain After Photodynamic Therapy: A Case Report with a 22-Year Follow-Up.

Objective

Recurrence or redarkening of port-wine stain (PWS) after laser treatment occurs frequently.

Background

Vascular-targeted photodynamic therapy (PDT) is an alternative adjuvant treatment for PWS.

Methods

We report the first case of PWS recurrence after PDT with a 22-year follow-up.

Results

Histological analysis was performed to indicate the possible mechanisms of PWS recurrence.

Conclusions

This case demonstrates the possibility of PWS recurrence and suggests that patients be notified of this possibility before treatment.