Conjugated estrogens (Premarin) vaginal cream.

An old conjugated estrogens vaginal cream (Premarin Vaginal Cream--Wyeth) has been newly approved by the FDA specifically for treatment of moderate to severe dyspareunia due to vulvar and vaginal atrophy associated with menopause. Synthetic conjugated estrogens A vaginal cream (Barr) has also been approved for this indication, but has not yet been marketed.