British journal of obstetrics and gynaecology · 1993
Antithyroid antibodies underlying thyroid abnormalities and miscarriage or pregnancy induced hypertension.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lejeune B, Grun J P, de Nayer P, Servais G, Glinoer D
Аннотация
OBJECTIVE: To assess whether asymptomatic abnormalities, including thyroid auto-antibodies, were associated with an abnormal miscarriage rate or a poor obstetric outcome.
DESIGN: Prospective study of thyroid auto-antibodies and thyroid function in an unselected obstetric population.
SETTING: Saint-Pierrie Hospital, Brussels, Belgium.
SUBJECTS: Seven hundred and thirty consecutive pregnant women attending the antenatal clinic.
MAIN OUTCOME MEASURES: Miscarriage and pregnancy induced hypertension.
RESULTS: Elevated antithyroperoxidase (TPO-Ab) and antithyroglobulin (TG-Ab) antibody titres are associated with an increased miscarriage rate. Also, asymptomatic thyroid abnormalities, mainly abnormal echo-structure but not antithyroid antibodies, are associated with pregnancy induced hypertension.
CONCLUSION: The presence of thyroid auto-antibodies during pregnancy constitutes a marker of increased risk of miscarriage and poor obstetric prognosis.
DESIGN: Prospective study of thyroid auto-antibodies and thyroid function in an unselected obstetric population.
SETTING: Saint-Pierrie Hospital, Brussels, Belgium.
SUBJECTS: Seven hundred and thirty consecutive pregnant women attending the antenatal clinic.
MAIN OUTCOME MEASURES: Miscarriage and pregnancy induced hypertension.
RESULTS: Elevated antithyroperoxidase (TPO-Ab) and antithyroglobulin (TG-Ab) antibody titres are associated with an increased miscarriage rate. Also, asymptomatic thyroid abnormalities, mainly abnormal echo-structure but not antithyroid antibodies, are associated with pregnancy induced hypertension.
CONCLUSION: The presence of thyroid auto-antibodies during pregnancy constitutes a marker of increased risk of miscarriage and poor obstetric prognosis.