Pediatrics international : official journal of the Japan Pediatric Society · 2014
Predictive value of gelsolin for the outcomes of preterm neonates: a pilot study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Kose Mehmet, Elmas Tuba, Gokahmetoglu Selma, Ozturk Mehmet Adnan, Ekinci Duygu, Elmali Ferhan, Halis Hulya, Bastug Osman
Аннотация
BACKGROUND: Plasma gelsolin is a circulating actin-binding protein that has a protective role against tissue injuries. Our aim was to compare the baseline levels of gelsolin in premature infants with neonatal outcomes.
METHODS: A total of 32 preterm neonates born at 23-32 weeks of gestation were enrolled in the study.
RESULTS: Plasma gelsolin levels at 72 h were significantly lower in patients with respiratory distress syndrome, in patients who were administered surfactant therapy and in patients who developed sepsis (P < 0.05). Plasma gelsolin levels at 28 days were significantly lower in patients who developed bronchopulmonary dysplasia and retinopathy of prematurity (P < 0.05).
CONCLUSIONS: Low plasma gelsolin levels in the first postnatal month may be associated with poor outcomes in premature infants.
METHODS: A total of 32 preterm neonates born at 23-32 weeks of gestation were enrolled in the study.
RESULTS: Plasma gelsolin levels at 72 h were significantly lower in patients with respiratory distress syndrome, in patients who were administered surfactant therapy and in patients who developed sepsis (P < 0.05). Plasma gelsolin levels at 28 days were significantly lower in patients who developed bronchopulmonary dysplasia and retinopathy of prematurity (P < 0.05).
CONCLUSIONS: Low plasma gelsolin levels in the first postnatal month may be associated with poor outcomes in premature infants.